Description

(3-(Pyrazin-2-Yl)-1,2,4-Oxadiazol-5-Yl)Methanamine is a high-purity heterocyclic building block featuring a fused pyrazine-oxadiazole core structure. This compound is of significant value in pharmaceutical research and development, serving as a key synthetic intermediate for the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead compound generation and structure-activity relationship (SAR) studies due to its privileged heterocyclic scaffold.
• Agrochemical Development: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis or material science.
• Advanced Material Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	(3-(Pyrazin-2-Yl)-1,2,4-Oxadiazol-5-Yl)Methanamine
CAS No.	1157834-49-5
Molecular Formula	C7H7N5O
Molecular Weight	177.16 g/mol
Synonyms	5-(Aminomethyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole; 2-[(5-Aminomethyl)-1,2,4-oxadiazol-3-yl]pyrazine; (3-Pyrazin-2-yl-1,2,4-oxadiazol-5-yl)methanamine; 1,2,4-Oxadiazole-5-methanamine, 3-(2-pyrazinyl)-; 1157834-49-5; (3-(Pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)methylamine
EINECS	Contact for details

Quality Control

Our (3-(Pyrazin-2-Yl)-1,2,4-Oxadiazol-5-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.