Description

1-(5-Bromo-2-Methylphenyl)Piperidin-2-One is a specialized organic building block featuring a brominated aromatic ring fused with a lactam (piperidin-2-one) moiety. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams seeking to develop new active compounds, particularly in medicinal chemistry for creating novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science: Acts as a precursor for advanced polymers and liquid crystals, where the bromine atom offers a site for further functionalization.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical spaces in organic synthesis.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	1-(5-Bromo-2-Methylphenyl)Piperidin-2-One
CAS No.	1157455-49-6
Molecular Formula	C12H14BrNO
Molecular Weight	268.15 g/mol
Synonyms	1-(5-Bromo-2-methylphenyl)piperidin-2-one; 1-(5-Bromo-o-tolyl)piperidin-2-one; 2-Piperidinone, 1-(5-bromo-2-methylphenyl)-; 5-Bromo-2-methyl-1-(2-oxopiperidin-1-yl)benzene; 1-(5-Bromo-2-methylphenyl)-2-piperidinone; 1157455-49-6
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-2-Methylphenyl)Piperidin-2-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide documentation to meet the rigorous demands of pharmaceutical and agrochemical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.