Description

Methyl 2-[(6-Chloropyrazin-2-Yl)Sulfanyl]Acetate CAS NO 1156664-80-0 is a high-purity, synthetically valuable heterocyclic building block featuring a chloropyrazine core linked via a thioether bridge to a methyl ester functional group. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the efficient synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, crop protection, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Serves as a building block for creating next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Used to synthesize molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Employed in the synthesis of specialized ligands and functional organic molecules for electronic or catalytic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new chemical space.

Basic Information

Product Name	Methyl 2-[(6-Chloropyrazin-2-Yl)Sulfanyl]Acetate
CAS No.	1156664-80-0
Molecular Formula	C7H7ClN2O2S
Molecular Weight	218.66 g/mol
Synonyms	Methyl (6-chloropyrazin-2-ylthio)acetate; 2-[(6-Chloro-2-pyrazinyl)thio]acetic acid methyl ester; Acetic acid, 2-[(6-chloro-2-pyrazinyl)thio]-, methyl ester; Methyl 2-((6-chloropyrazin-2-yl)thio)acetate; 1156664-80-0; Methyl 2-(6-chloropyrazin-2-ylsulfanyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-[(6-Chloropyrazin-2-Yl)Sulfanyl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can support development projects requiring compliance with ICH guidelines for impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.