Description

3-[4-(3,4-Dichlorobenzyl)Piperazin-1-Yl]Propanoic Acid is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D teams and custom synthesis specialists focused on creating new therapeutic agents, particularly in neurological and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting GPCRs (G-protein-coupled receptors).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized building block for the production of high-value, complex molecules on a commercial scale.
• Biochemical Tool Compound: Potential use in the development of research reagents and probes for studying biological pathways.
• Agrochemical Research: Exploration of applications in the development of new crop protection agents.

Basic Information

Product Name	3-[4-(3,4-Dichlorobenzyl)Piperazin-1-Yl]Propanoic Acid
CAS No.	1155622-26-6
Molecular Formula	C14H18Cl2N2O2
Molecular Weight	317.21 g/mol
Synonyms	3-[4-[(3,4-Dichlorophenyl)methyl]piperazin-1-yl]propanoic acid; 1-(3,4-Dichlorobenzyl)-4-(2-carboxyethyl)piperazine; 3-(4-((3,4-Dichlorobenzyl)piperazin-1-yl)propanoic acid; 1155622-26-6; 3-(4-(3,4-Dichlorobenzyl)piperazin-1-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-[4-(3,4-Dichlorobenzyl)Piperazin-1-Yl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.