Description

2-(4-(4-Amino-2-Fluorophenyl)Piperazin-1-Yl)Ethanol is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a unique scaffold for molecular diversification. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its fluorinated aromatic and piperazine structure.
• Ligand Synthesis: Serves as a versatile starting material for creating novel ligands in catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The ethanolamine side chain and aromatic amine group facilitate its use in linker chemistry for antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent or affinity probes for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	2-(4-(4-Amino-2-Fluorophenyl)Piperazin-1-Yl)Ethanol
CAS No.	1155522-89-6
Molecular Formula	C12H18FN3O
Molecular Weight	239.29 g/mol
Synonyms	1-(2-Hydroxyethyl)-4-(4-amino-2-fluorophenyl)piperazine; 4-(4-Amino-2-fluorophenyl)-1-(2-hydroxyethyl)piperazine; 2-[4-(4-Amino-2-fluorophenyl)piperazin-1-yl]ethanol; 2-(4-(4-Amino-2-fluorophenyl)-1-piperazinyl)ethanol; 1155522-89-6; 4-Amino-2-fluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]benzene
EINECS	Contact for details

Quality Control

Our 2-(4-(4-Amino-2-Fluorophenyl)Piperazin-1-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, including cGMP-compliant synthesis for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.