Description

4-(4-Amino-3-Methylphenyl)-2-Piperazinone is a specialized aromatic amine derivative featuring a piperazinone moiety, serving as a high-value pharmaceutical intermediate and fine chemical building block. Its molecular structure makes it a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and advanced agrochemical sectors seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel psychoactive pharmaceuticals and neuroleptic agents.
• API Synthesis: Core precursor for the development of Active Pharmaceutical Ingredients (APIs) with complex heterocyclic architectures.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Intermediates: Potential intermediate in the synthesis of advanced crop protection agents and herbicides.
• Dye & Pigment Chemistry: Serves as an intermediate for producing specialized azo dyes and high-performance pigments.
• Material Science: Building block for advanced polymers and functional materials requiring aromatic amine components.

Basic Information

Product Name	4-(4-Amino-3-Methylphenyl)-2-Piperazinone
CAS No.	1154320-00-9
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	2-Piperazinone, 4-(4-amino-3-methylphenyl)-; 4-(4-Amino-3-methylphenyl)piperazin-2-one; 1-(4-Amino-3-methylphenyl)piperazin-2-one; 4-(4-Amino-3-methylphenyl)-2-piperazinone; 4-(4-Amino-3-methylphenyl)-1,4-diazepan-2-one; 1154320-00-9; 4-(4-Amino-3-methylphenyl)piperazinone
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-3-Methylphenyl)-2-Piperazinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques such as HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. We are committed to meeting the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.