Description

(2S,5S)-1,2,5-Trimethylpiperazine is a high-purity, stereochemically defined chiral piperazine derivative. This compound serves as a critical chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and antiviral agents.
• Asymmetric Catalyst Ligand: Used as a ligand for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and other catalytic transformations.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: A versatile building block for creating complex, high-value chiral molecules for specialty chemical applications.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	(2S,5S)-1,2,5-Trimethylpiperazine
CAS No.	1152368-06-3
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(2S,5S)-1,2,5-Trimethylpiperazine; (2S,5S)-1,2,5-TMP; (2S,5S)-TMP; (S,S)-1,2,5-Trimethylpiperazine; 1,2,5-Trimethylpiperazine, (2S,5S)-; Piperazine, 1,2,5-trimethyl-, (2S,5S)-; (2S,5S)-1,2,5-TMPIP; (S,S)-TMP
EINECS	Contact for details

Quality Control

Our (2S,5S)-1,2,5-Trimethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.