Description

(2S,5R)-1,2,5-Trimethylpiperazine is a high-purity, stereochemically defined chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its precise stereochemistry makes it an invaluable intermediate for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Synthesis: Building block for developing enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Intermediate in the manufacture of complex specialty chemicals, dyes, and performance materials.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological development and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial production of chiral molecules.

Basic Information

Product Name	(2S,5R)-1,2,5-Trimethylpiperazine
CAS No.	1152367-85-5
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(2S,5R)-1,2,5-Trimethylpiperazine; (2S,5R)-1,2,5-TMP; (2S,5R)-1,2,5-TMPP; (2S,5R)-1,2,5-Trimethyl-piperazine; (2S,5R)-1,2,5-Trimethylhexahydropyrazine; 1,2,5-Trimethylpiperazine, (2S,5R)-; Piperazine, 1,2,5-trimethyl-, (2S,5R)-
EINECS	Contact for details

Quality Control

Our (2S,5R)-1,2,5-Trimethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.