Description

2-Bromo-7-Chloro-5H-Pyrrolo[2,3-B]Pyrazine is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules. The precise bromo and chloro substitutions on the fused pyrrolopyrazine core offer unique reactivity for selective cross-coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Research: Building block for developing novel herbicides and fungicides with specific modes of action.
• Material Science: Used in the creation of organic semiconductors and electronic materials due to its electron-deficient heterocyclic structure.
• Chemical Biology: Serves as a molecular scaffold for designing probes and tool compounds to study biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Bromo-7-Chloro-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	1150617-58-5
Molecular Formula	C6H3BrClN3
Molecular Weight	232.47 g/mol
Synonyms	2-Bromo-7-chloro-5H-pyrrolo[2,3-b]pyrazine; 7-Chloro-2-bromo-5H-pyrrolo[2,3-b]pyrazine; 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-chloro-; 1150617-58-5; 2-Bromo-7-chloro-5H-pyrrolo[2,3-b]pyrazine; Pyrrolo[2,3-b]pyrazine, 2-bromo-7-chloro-5H-
EINECS	Contact for details

Quality Control

Our 2-Bromo-7-Chloro-5H-Pyrrolo[2,3-B]Pyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.