Description

tert-Butyl(R)-3-((6-Chloropyrazin-2-Yl)Oxy)Piperidine-1-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for medicinal chemistry research and process development, offering a versatile scaffold for constructing complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Medicinal Chemistry: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Used in route scouting and scale-up synthesis for the production of candidate drugs during clinical development phases.
• Asymmetric Synthesis: The (R)-configured piperidine core is valuable for introducing stereochemical complexity in synthetic pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Product Name	tert-Butyl(R)-3-((6-Chloropyrazin-2-Yl)Oxy)Piperidine-1-Carboxylate
CAS No.	1147998-31-9
Molecular Formula	C14H18ClN3O3
Molecular Weight	311.76 g/mol
Synonyms	1-Boc-3-((6-chloropyrazin-2-yl)oxy)-(R)-piperidine; (R)-1-(tert-Butoxycarbonyl)-3-((6-chloropyrazin-2-yl)oxy)piperidine; (R)-tert-Butyl 3-((6-chloropyrazin-2-yl)oxy)piperidine-1-carboxylate; tert-Butyl (3R)-3-[(6-chloropyrazin-2-yl)oxy]piperidine-1-carboxylate; 1147998-31-9; (R)-Boc-3-(6-chloropyrazin-2-yloxy)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl(R)-3-((6-Chloropyrazin-2-Yl)Oxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.