Description

2,2,2-Trifluoro-1-Pyrazin-2-Yl-Ethanone is a high-value fluorinated pyrazine derivative, serving as a critical building block in modern synthetic chemistry. Its trifluoroacetyl group attached to a pyrazine heterocycle makes it a versatile intermediate for introducing fluorine atoms and nitrogen-containing heterocycles into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyrazine moiety for biological activity.
• Material Science Research: Acts as a precursor for synthesizing fluorinated organic materials, including liquid crystals and specialty polymers.
• Chemical Biology & Proteomics: Employed as a reactive handle or labeling agent in the study of biological systems and protein interactions.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic compounds through reactions like nucleophilic substitution and cross-coupling.

Basic Information

Product Name	2,2,2-Trifluoro-1-Pyrazin-2-Yl-Ethanone
CAS No.	1147103-48-7
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	2,2,2-Trifluoro-1-(pyrazin-2-yl)ethanone; 2-(Trifluoroacetyl)pyrazine; 2-Pyrazinyl Trifluoromethyl Ketone; 1-(Pyrazin-2-yl)-2,2,2-trifluoroethanone; 2-Trifluoroacetylpyrazine; Ethanone, 2,2,2-trifluoro-1-(2-pyrazinyl)-; Trifluoromethyl 2-pyrazinyl ketone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Pyrazin-2-Yl-Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) are available for every batch upon request, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.