Description

4-(3,5-Difluorophenyl)Piperidin-4-Ol Hcl CAS NO 1146363-03-2 is a high-purity, fluorinated piperidine derivative used as a critical pharmaceutical intermediate. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex, fluorinated APIs.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and chemical biology projects.

Basic Information

Product Name	4-(3,5-Difluorophenyl)Piperidin-4-Ol Hcl
CAS No.	1146363-03-2
Molecular Formula	C11H14ClF2NO
Molecular Weight	249.69 g/mol
Synonyms	4-(3,5-Difluorophenyl)-4-hydroxypiperidine hydrochloride; 4-(3,5-Difluorophenyl)-4-piperidinol hydrochloride; 4-Hydroxy-4-(3,5-difluorophenyl)piperidine hydrochloride; 4-Piperidinol, 4-(3,5-difluorophenyl)-, hydrochloride; 1-(3,5-Difluorophenyl)-4-piperidinol hydrochloride; 1146363-03-2 (CAS); 4-(3,5-Difluorophenyl)piperidin-4-ol HCl
EINECS	Contact for details

Quality Control

Our 4-(3,5-Difluorophenyl)Piperidin-4-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.