Description

tert-Butyl 3-(Pyrazin-2-yl)azetidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile building block for constructing complex molecular architectures, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in the scale-up and route development for the commercial synthesis of active pharmaceutical ingredients (APIs).
• Chemical Biology: Serves as a precursor for designing molecular probes and tool compounds to study biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 3-(Pyrazin-2-yl)azetidine-1-carboxylate
CAS No.	1146085-63-3
Molecular Formula	C12H17N3O2
Molecular Weight	235.28 g/mol
Synonyms	1-Boc-3-(pyrazin-2-yl)azetidine; tert-Butyl 3-pyrazin-2-ylazetidine-1-carboxylate; 3-(Pyrazin-2-yl)azetidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(pyrazin-2-yl)azetidine; Azetidine-1-carboxylic acid, 3-(2-pyrazinyl)-, 1,1-dimethylethyl ester; 1146085-63-3; Boc-3-(2-pyrazinyl)azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Pyrazin-2-yl)azetidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.