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[1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester, 98+% C16H26N4O2, Mw: 306.41 CAS NO 1146080-78-5


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CAS No.:1146080-78-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity (98+%) advanced pharmaceutical intermediate with the molecular formula C16H26N4O2 and a molecular weight of 306.41. This compound is a critical building block in modern medicinal chemistry, valued for its piperidine and pyrazine motifs which are prevalent in bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

  • Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
  • CNS Drug Development: A valuable scaffold for creating compounds targeting neurological receptors and enzymes.
  • Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
  • Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name [1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No. 1146080-78-5
Molecular Formula C16H26N4O2
Molecular Weight 306.41 g/mol
Synonyms tert-Butyl N-[1-(2-pyrazin-1-ylethyl)piperidin-4-yl]carbamate; 1-(1-Pyrazin-2-ylethyl)piperidin-4-amine, N-BOC-protected; BOC-4-[[1-(2-Pyrazinyl)ethyl]amino]piperidine; N-Boc-1-(1-pyrazin-2-ylethyl)piperidin-4-amine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(2-pyrazinylethyl)piperidine; (1-(1-Pyrazin-2-yl-ethyl)-piperidin-4-yl)-carbamic acid tert-butyl ester
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Quality Control

Our [1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and identity. Standard testing includes HPLC for assay and purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture content. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) 98.0% min
Water Content (KF) 0.5% max
Residual Solvents (GC) Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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