Description

1-(4-Chloro-Phenyl)-2-(3-Hydroxy-Piperidin-1-Yl)-Ethanone is a high-purity (98+%) organic building block with the molecular formula C13H16ClNO2 and a molecular weight of 253.73. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, offering a unique structural motif that combines a chlorophenyl ketone with a hydroxypiperidine moiety. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical and agrochemical industries for the creation of new active ingredients. The CAS number for this compound is 1146080-72-9.

Application

This versatile chemical intermediate is designed for advanced synthetic applications, particularly in regulated industries where purity and consistency are paramount.

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides due to its bioactive scaffold.
• Chemical Synthesis: Serves as a precursor for more complex heterocyclic compounds in academic and industrial research laboratories.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecules.

Basic Information

Product Name	1-(4-Chloro-Phenyl)-2-(3-Hydroxy-Piperidin-1-Yl)-Ethanone
CAS No.	1146080-72-9
Molecular Formula	C13H16ClNO2
Molecular Weight	253.73 g/mol
Synonyms	1-(4-Chlorophenyl)-2-(3-hydroxypiperidin-1-yl)ethanone; 2-(3-Hydroxy-1-piperidinyl)-1-(4-chlorophenyl)ethanone; 1-(4-Chlorophenyl)-2-(3-hydroxy-1-piperidinyl)ethanone; 1146080-72-9; Ethanone, 1-(4-chlorophenyl)-2-(3-hydroxy-1-piperidinyl)-; 3-Hydroxy-1-[2-(4-chlorophenyl)-2-oxoethyl]piperidine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Phenyl)-2-(3-Hydroxy-Piperidin-1-Yl)-Ethanone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and is free from critical impurities. Comprehensive Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are provided and available upon request, supporting compliance in GMP-oriented applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.