Description

(3-Chloromethyl-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone, 98+% C11H14Cln3O, Mw: 239.71 CAS NO 1146080-48-9 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core linked to a pyrazine moiety via a carbonyl bridge. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with potential activity in central nervous system and other therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.
• Library Synthesis: A valuable component for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	(3-Chloromethyl-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone
CAS No.	1146080-48-9
Molecular Formula	C11H14ClN3O
Molecular Weight	239.71 g/mol
Synonyms	1-[(3-Chloromethyl)piperidin-1-yl]-2-pyrazinylmethanone; (3-Chloromethyl-1-piperidinyl)(2-pyrazinyl)methanone; 2-Pyrazinecarboxylic acid (3-chloromethyl-1-piperidinyl) ester; 1146080-48-9; (3-Chloromethylpiperidin-1-yl)(pyrazin-2-yl)methanone; Pyrazin-2-yl(3-chloromethylpiperidin-1-yl)methanone
EINECS	Contact for details

Quality Control

Our (3-Chloromethyl-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the purity meets or exceeds 98% and identity is confirmed. Certificates of Analysis (COA) with full analytical data are provided for every shipment to guarantee traceability and batch-to-batch consistency essential for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.