Description

2-Chloro-N-[1-(4-Fluoro-Benzoyl)-Piperidin-3-Yl]-Acetamide is a high-purity (98+%) synthetic organic compound with the molecular formula C14H16ClFN2O2 and a molecular weight of 298.75. This compound serves as a critical pharmaceutical intermediate or research chemical in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways. It is essential for medicinal chemistry research, process development, and scale-up activities within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing piperidine and fluorinated benzoyl motifs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a standard or starting material for optimizing synthetic routes and manufacturing processes under GMP conditions.
• Biochemical Research: Potential use as a tool compound or ligand in probing enzyme inhibition or receptor binding studies.
• Custom Synthesis: A versatile precursor for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	2-Chloro-N-[1-(4-Fluoro-Benzoyl)-Piperidin-3-Yl]-Acetamide
CAS No.	1146080-30-9
Molecular Formula	C14H16ClFN2O2
Molecular Weight	298.75 g/mol
Synonyms	2-Chloro-N-(1-(4-fluorobenzoyl)piperidin-3-yl)acetamide; 1-(4-Fluorobenzoyl)-3-[(2-chloroacetyl)amino]piperidine; 3-[(2-Chloroacetyl)amino]-1-(4-fluorobenzoyl)piperidine; 1146080-30-9; Acetamide, 2-chloro-N-[1-(4-fluorobenzoyl)-3-piperidinyl]-; 2-Chloro-N-(1-(4-fluorobenzoyl)piperidin-3-yl)ethanamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[1-(4-Fluoro-Benzoyl)-Piperidin-3-Yl]-Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system is designed to support research and development as well as pre-clinical scale requirements, with specifications that can be aligned with customer-specific needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.