Description

2-Chloro-n-[1-(2-Fluoro-Benzoyl)-Piperidin-4-Yl]-Acetamide is a high-purity (98+%) organic intermediate with the molecular formula C14H16ClFN2O2 and a molecular weight of 298.75. This compound is a critical building block in modern pharmaceutical research and development, valued for its piperidine and fluorinated benzoyl motifs. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Agrochemical Development: Serves as a building block for creating novel pesticides or herbicides, leveraging its halogenated structure.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis and methodological studies.

Basic Information

Product Name	2-Chloro-n-[1-(2-Fluoro-Benzoyl)-Piperidin-4-Yl]-Acetamide
CAS No.	1146080-29-6
Molecular Formula	C14H16ClFN2O2
Molecular Weight	298.75 g/mol
Synonyms	2-Chloro-N-[1-(2-fluorobenzoyl)piperidin-4-yl]acetamide; 2-Chloro-N-(1-(2-fluorobenzoyl)piperidin-4-yl)acetamide; 2-Chloroacetamide, N-[1-(2-fluorobenzoyl)-4-piperidinyl]-; 1146080-29-6; N-(1-(2-Fluorobenzoyl)piperidin-4-yl)-2-chloroacetamide; 2-Chloro-N-(1-(2-fluorobenzoyl)piperidin-4-yl)acetamide; Acetamide, 2-chloro-N-[1-(2-fluorobenzoyl)-4-piperidinyl]-
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-[1-(2-Fluoro-Benzoyl)-Piperidin-4-Yl]-Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.