Description

2-(4-Chlorophenoxy)-1-(Piperazin-1-Yl)Ethan-1-One Hydrochloride is a high-purity organic salt compound, primarily valued as a critical pharmaceutical intermediate. Its molecular structure, featuring a chlorophenoxy moiety linked to a piperazine ring, makes it a versatile building block for synthesizing more complex active pharmaceutical ingredients (APIs). This compound is essential for research and development laboratories and production facilities in the life sciences sector requiring reliable, high-quality chemical precursors.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and commercial synthesis of novel drug candidates, particularly in central nervous system (CNS) and antimicrobial therapeutic areas.
• Chemical Research & Development: Used as a standardized building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production processes of target APIs, where consistent quality is paramount.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing in pharmaceutical analysis.
• Biochemical Research: Utilized in biochemical assays and as a tool compound for investigating biological pathways and receptor interactions.

Basic Information

Product Name	2-(4-Chlorophenoxy)-1-(Piperazin-1-Yl)Ethan-1-One Hydrochloride
CAS No.	1144037-44-4
Molecular Formula	C12H16ClN2O2•HCl
Molecular Weight	301.63 g/mol (for hydrochloride salt)
Synonyms	1-[2-(4-Chlorophenoxy)acetyl]piperazine hydrochloride; 2-(4-Chlorophenoxy)-1-(piperazin-1-yl)ethanone hydrochloride; 4-Chlorophenoxy(piperazin-1-yl)methanone hydrochloride; 1-(4-Chlorophenoxyacetyl)piperazine HCl; 2-(p-Chlorophenoxy)-1-piperazin-1-ylethanone hydrochloride; N-(4-Chlorophenoxyacetyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenoxy)-1-(Piperazin-1-Yl)Ethan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.