Description

2,2-Dimethyl-3-[(4-Methyl-1,4-Diazepan-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropane and diazepane fused structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) and potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained cyclopropane ring and functionalized heterocycle.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material or intermediate for contract research organizations (CROs) and CDMOs producing specialized compounds on a kilogram scale.
• Protease Inhibitor Development: Its structural motifs suggest potential application in the development of inhibitors targeting specific enzymes.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2,2-Dimethyl-3-[(4-Methyl-1,4-Diazepan-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid
CAS No.	1142215-33-5
Molecular Formula	C14H22N2O3
Molecular Weight	266.34 g/mol
Synonyms	1-(2,2-Dimethyl-3-(carboxy)cyclopropanoyl)-4-methylhomopiperazine; 2,2-Dimethyl-3-[(4-methyl-1,4-diazepan-1-yl)carbonyl]cyclopropanecarboxylic acid; 2,2-Dimethyl-3-(4-methyl-1,4-diazepane-1-carbonyl)cyclopropanecarboxylic acid; 3-[(4-Methyl-1,4-diazepan-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid; CAS 1142215-33-5; 1-(2,2-Dimethyl-3-carboxycyclopropanoyl)-4-methylhomopiperazine
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-3-[(4-Methyl-1,4-Diazepan-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.