Description

2,2-Dimethyl-3-[(4-Methylpiperazin-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid is a high-value, synthetically advanced chemical intermediate characterized by its unique cyclopropane and piperazine-containing structure. This compound is critical for research and development in pharmaceutical chemistry, serving as a sophisticated building block for novel active ingredients. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, targeted molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS or anti-infective therapies.
• Chemical Synthesis: Used in advanced organic synthesis to introduce the constrained cyclopropane ring and functionalized piperazine moiety into more complex molecular architectures.
• Research & Development: Serves as a critical reference standard and starting material in academic and industrial research for studying structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs) during development phases.

Basic Information

Product Name	2,2-Dimethyl-3-[(4-Methylpiperazin-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid
CAS No.	1142214-55-8
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	2,2-Dimethyl-3-(4-methylpiperazine-1-carbonyl)cyclopropane-1-carboxylic acid; 1-(2,2-Dimethyl-3-(carboxy)cyclopropanoyl)-4-methylpiperazine; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-[(4-methyl-1-piperazinyl)carbonyl]-; 1142214-55-8; (2,2-Dimethyl-3-((4-methylpiperazin-1-yl)carbonyl)cyclopropyl)formic acid
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-3-[(4-Methylpiperazin-1-Yl)Carbonyl]Cyclopropanecarboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.