Description

tert-Butyl 4-[3-(Methoxycarbonyl)-4-Nitrophenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate is a sophisticated, high-purity organic intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block in the synthesis of complex molecules, enabling the creation of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities during process R&D.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 4-[3-(Methoxycarbonyl)-4-Nitrophenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	1135283-55-4
Molecular Formula	C18H25N3O6
Molecular Weight	379.41 g/mol
Synonyms	1-Boc-4-(2-methoxycarbonyl-5-nitrophenyl)piperazine; tert-Butyl 4-(2-(methoxycarbonyl)-5-nitrophenyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-methoxycarbonyl-5-nitrophenyl)piperazine; 4-(2-Methoxycarbonyl-5-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-methoxycarbonyl-5-nitrophenyl)piperazine; Boc-4-(2-COOMe-5-NO2-Ph)-piperazine; 1135283-55-4
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-[3-(Methoxycarbonyl)-4-Nitrophenyl]Tetrahydro-1(2H)-Pyrazinecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.