Description

(R)-1-Cyclohexyl-2-Methyl-Piperazine Dihydrochloride is a high-purity chiral piperazine derivative, supplied as a stable dihydrochloride salt. This compound is a critical chiral building block and intermediate for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutics. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical synthesis industries seeking to introduce specific stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis and metal complexation.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of enantiomerically pure compounds.
• Academic & Industrial R&D: Utilized in research programs focused on discovering new bioactive molecules with defined stereocenters.

Basic Information

Product Name	(R)-1-Cyclohexyl-2-Methyl-Piperazine Dihydrochloride
CAS No.	1134603-02-3
Molecular Formula	C11H24Cl2N2
Molecular Weight	255.23 g/mol
Synonyms	(R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride; (R)-2-Methyl-1-cyclohexylpiperazine dihydrochloride; (R)-1-Cyclohexyl-2-methylpiperazine hydrochloride (1:2); (2R)-1-Cyclohexyl-2-methylpiperazine dihydrochloride; (R)-1-Cyclohexyl-2-methyl-piperazine dihydrochloride; (R)-1-Cyclohexyl-2-methylpiperazine 2HCl; (R)-CMHP dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Cyclohexyl-2-Methyl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.