Description

2-(4-Methylphenyl)-1,3-Dioxoisoindoline-5-Carbonyl Chloride is a high-purity, reactive chemical intermediate featuring a carbonyl chloride functional group attached to a phthalimide-derived core. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, enabling the formation of amide bonds under mild conditions. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those containing phthalimide or isoindoline moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as an acylating agent in peptide coupling and other amide bond formation reactions in laboratory settings.
• Material Science Research: Potential precursor for the development of specialty polymers, dyes, and photoactive materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes.

Basic Information

Product Name	2-(4-Methylphenyl)-1,3-Dioxoisoindoline-5-Carbonyl Chloride
CAS No.	1134335-00-4
Molecular Formula	C16H10ClNO3
Molecular Weight	299.71 g/mol
Synonyms	5-(Chlorocarbonyl)-2-(p-tolyl)isoindoline-1,3-dione; 2-(p-Tolyl)-1,3-dioxoisoindoline-5-carbonyl chloride; 1,3-Dioxo-2-(4-methylphenyl)isoindoline-5-carbonyl chloride; N-(4-Methylphenyl)phthalimide-5-carbonyl chloride; 5-Carboxyphthalimide p-toluidide acid chloride; 1134335-00-4; 2-(4-Methylphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Methylphenyl)-1,3-Dioxoisoindoline-5-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.