Description

Methyl 3-(1-Benzyl-4-{4-[3-(Trifluoromethyl)-Phenyl]Piperazin-1-Yl}Piperidin-3-Yl)Propanoate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, potent therapeutic agents targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for neurological and psychiatric applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of investigational drugs, particularly those acting on neurotransmitter receptors.
• Neurological Research: Used in the discovery and development of potential treatments for conditions such as schizophrenia, depression, and anxiety disorders.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Preclinical Development: Supplied in bulk for the production of Active Pharmaceutical Ingredients (APIs) required for toxicology and early-phase clinical studies.
• Contract Research & Manufacturing (CRO/CMO): A key material for organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Methyl 3-(1-Benzyl-4-{4-[3-(Trifluoromethyl)-Phenyl]Piperazin-1-Yl}Piperidin-3-Yl)Propanoate
CAS No.	1134331-53-5
Molecular Formula	C27H34F3N3O2
Molecular Weight	489.58 g/mol
Synonyms	Methyl 3-(1-benzyl-4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)piperidin-3-yl)propanoate; 1-Benzyl-4-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-3-piperidinepropanoic Acid Methyl Ester; 3-(1-Benzyl-4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)piperidin-3-yl)propanoic acid methyl ester; CAS 1134331-53-5
EINECS	Contact for details

Quality Control

Our Methyl 3-(1-Benzyl-4-{4-[3-(Trifluoromethyl)-Phenyl]Piperazin-1-Yl}Piperidin-3-Yl)Propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.