Description

3-Piperidinepropanoic Acid, 4-[4-(2-Methoxyphenyl)-1-Piper is a high-purity, non-natural amino acid derivative and a sophisticated piperidine-based building block. This compound is critical for pharmaceutical research and development, serving as a key chiral intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel therapeutic candidates, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry & Scale-up: Serves as a starting material or advanced intermediate in the development of scalable, GMP-compliant synthetic routes.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes, biomarkers, and targeted drug delivery systems due to its functionalizable carboxylic acid group.
• Asymmetric Synthesis: Employed as a chiral auxiliary or scaffold in enantioselective synthesis to introduce stereochemical complexity.
• Chemical Biology: Incorporated into peptide mimetics and other bioactive compounds to modulate protein-protein interactions.

Basic Information

Product Name	3-Piperidinepropanoic Acid, 4-[4-(2-Methoxyphenyl)-1-Piper
CAS No.	1134331-51-3
Molecular Formula	C19H27NO3
Molecular Weight	317.42 g/mol
Synonyms	4-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-piperidin-1-ylpropanoic acid; 3-(Piperidin-1-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanoic acid (tautomeric form); 4-(4-(2-Methoxyphenyl)piperazin-1-yl)-3-(piperidin-1-yl)butanoic acid; 1134331-51-3; UNII-8V4A3N2AI2; 8V4A3N2AI2; 4-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-piperidinyl)-1-butanoic acid
EINECS	Contact for details

Quality Control

Our 3-Piperidinepropanoic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided for every shipment, ensuring traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.