Description

Methyl 4-(3-Methylpiperazin-1-Yl)Benzoate is a high-purity organic compound featuring a benzoate ester core linked to a substituted piperazine moiety. This structure makes it a valuable key pharmaceutical intermediate for the synthesis of more complex active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for candidates targeting neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) active compounds.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for potential APIs requiring a substituted piperazine-benzoate scaffold.
• Biochemical Research: Employed as a reference standard or reagent in pharmacological studies and receptor binding assays.
• Organic Synthesis: Functions as a versatile precursor for further chemical modifications, including hydrolysis to carboxylic acids or amide formation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Details
Product Name	Methyl 4-(3-Methylpiperazin-1-Yl)Benzoate
CAS No.	1131622-65-5
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	Methyl 4-(3-methyl-1-piperazinyl)benzoate; 4-(3-Methylpiperazin-1-yl)benzoic acid methyl ester; Benzoic acid, 4-(3-methyl-1-piperazinyl)-, methyl ester; Methyl p-(3-methylpiperazino)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(3-Methylpiperazin-1-Yl)Benzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation, assay, and impurity profiling. Certificates of Analysis (COA) detailing all test results are provided with each shipment. We support development and commercial projects with material suitable for research use or produced under current Good Manufacturing Practice (cGMP) guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.