Description

1-(4-Carboxyphenyl Methyl)-3-Ethyl-Piperazine is a specialized piperazine derivative featuring a carboxylic acid functional group, making it a versatile building block for advanced synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: The carboxylic acid group allows for incorporation into polymer chains to modify material properties for specialty coatings or adhesives.
• Bioconjugation and Linker Chemistry: Utilized in the design of chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Academic and R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	1-(4-Carboxyphenyl Methyl)-3-Ethyl-Piperazine
CAS No.	1131622-39-3
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	3-Ethyl-1-[(4-carboxyphenyl)methyl]piperazine; 1-[(4-Carboxyphenyl)methyl]-3-ethylpiperazine; 4-[(3-Ethylpiperazin-1-yl)methyl]benzoic acid; 1-(4-Carboxybenzyl)-3-ethylpiperazine; 3-Ethyl-1-(4-carboxybenzyl)piperazine; 1131622-39-3; 4-((3-Ethylpiperazin-1-yl)methyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Carboxyphenyl Methyl)-3-Ethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.