Description

5-Hydroxymethyl-Pyrazine-2-Carboxylic Acid Ethyl Ester is a high-purity pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its functional group versatility, enabling the construction of complex heterocyclic scaffolds essential for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the pyrazine core's bioactivity.
• Fine Chemical Production: Serves as a versatile precursor for synthesizing complex flavors, fragrances, and functional materials.
• Academic & Industrial R&D: Employed in medicinal chemistry and process chemistry research for structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Development: The hydroxymethyl and ester functionalities make it a useful starting material for creating novel chelating ligands and organocatalysts.

Basic Information

Product Name	5-Hydroxymethyl-Pyrazine-2-Carboxylic Acid Ethyl Ester
CAS No.	1131605-07-6
Molecular Formula	C9H12N2O3
Molecular Weight	196.20 g/mol
Synonyms	Ethyl 5-(hydroxymethyl)pyrazine-2-carboxylate; 5-Hydroxymethyl-2-pyrazinecarboxylic Acid Ethyl Ester; 2-Pyrazinecarboxylic acid, 5-(hydroxymethyl)-, ethyl ester; Ethyl 5-hydroxymethylpyrazine-2-carboxylate; 5-Hydroxymethylpyrazine-2-carboxylic acid ethyl ester; CAS 1131605-07-6
EINECS	Contact for details

Quality Control

Our 5-Hydroxymethyl-Pyrazine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting full specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.