Description

Ethyl 3-Bromo-4-(4-Methylpiperazin-1-Yl)Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its benzoate ester core functionalized with bromine and a methylpiperazine moiety. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where precise chemical structure and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new pharmacophores.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key fragment in constructing complex APIs, leveraging its bromine atom for further functionalization via cross-coupling reactions.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and scale-up projects under GMP or non-GMP conditions.
• Academic Research: Employed in university and institutional labs for pioneering synthetic methodology and heterocyclic chemistry studies.

Basic Information

Product Name	Ethyl 3-Bromo-4-(4-Methylpiperazin-1-Yl)Benzoate
CAS No.	1131594-69-8
Molecular Formula	C14H19BrN2O2
Molecular Weight	327.22 g/mol
Synonyms	Ethyl 3-bromo-4-(4-methyl-1-piperazinyl)benzoate; Benzoic acid, 3-bromo-4-(4-methyl-1-piperazinyl)-, ethyl ester; 3-Bromo-4-(4-methylpiperazin-1-yl)benzoic acid ethyl ester; 1131594-69-8; Ethyl 3-bromo-4-(N-methylpiperazinyl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-4-(4-Methylpiperazin-1-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high standards of chemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.