Description

(9Ar)-Octahydropyrazino[2,1-C][1,4]Oxazine Dihydrochloride is a high-purity, heterocyclic organic compound primarily utilized as a sophisticated pharmaceutical intermediate. This compound matters because it serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, particularly for central nervous system (CNS) and other specialty drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in neurological and psychiatric research.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct fused heterocyclic ring systems.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	(9Ar)-Octahydropyrazino[2,1-C][1,4]Oxazine Dihydrochloride
CAS No.	1126432-04-9
Molecular Formula	C8H16Cl2N2O
Molecular Weight	227.13 g/mol
Synonyms	Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride; (9aR)-Octahydro-2H-pyrazino[2,1-c][1,4]oxazine dihydrochloride; (R)-Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride; (9aR)-Octahydropyrazino[2,1-c][1,4]oxazine hydrochloride; 1,4-Oxazine, hexahydro-2H-pyrazino[2,1-c]-, dihydrochloride, (9aR)-; (R)-Hexahydro-2H-pyrazino[2,1-c][1,4]oxazine dihydrochloride
EINECS	Contact for details

Quality Control

Our (9Ar)-Octahydropyrazino[2,1-C][1,4]Oxazine Dihydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical development. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards, and custom synthesis under cGMP guidelines is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.