Description

3-(Trifluoromethyl)Piperidine Hydrochloride CAS NO 1124199-60-5 is a high-value, fluorinated piperidine derivative in its stable hydrochloride salt form, offering enhanced handling properties for advanced synthesis. This compound is a critical chiral building block and intermediate in modern pharmaceutical and agrochemical research, prized for its ability to introduce the metabolically stable trifluoromethyl group into complex molecules. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science: Employed in the research of advanced polymers and functional materials that require fluorinated components for specific properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and labeled compounds for studying biological mechanisms.

Basic Information

Product Name	3-(Trifluoromethyl)Piperidine Hydrochloride
CAS No.	1124199-60-5
Molecular Formula	C6H11ClF3N
Molecular Weight	189.61 g/mol
Synonyms	3-(Trifluoromethyl)piperidine HCl; 3-(Trifluoromethyl)piperidine hydrochloride; Piperidine, 3-(trifluoromethyl)-, hydrochloride (1:1); 3-Trifluoromethylpiperidine hydrochloride; α,α,α-Trifluoro-m-toluidine hydrochloride (related precursor); 3-CF3-Piperidine HCl
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.