Description

4-Piperidinecarbonitrile, 1-[[5-[4-Methyl-5-(Trifluoromethyl)-3-Isoxazolyl]-2-Thienyl]Carbonyl]- is a high-value, complex heterocyclic building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique structural motif for lead optimization. Pharmaceutical and agrochemical R&D organizations need this specialized chemical to accelerate their discovery pipelines and create new, patentable molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl and isoxazole moieties for enhanced bioactivity and environmental stability.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study enzyme function and protein-protein interactions in biological pathways.
• Material Science Precursor: Potential use in synthesizing specialty polymers or ligands for catalysts, utilizing its rigid, multi-heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical companies in their custom synthesis projects.

Basic Information

Product Name	4-Piperidinecarbonitrile, 1-[[5-[4-Methyl-5-(Trifluoromethyl)-3-Isoxazolyl]-2-Thienyl]Carbonyl]-
CAS No.	1124198-17-9
Molecular Formula	C16H12F3N3O2S
Molecular Weight	367.35 g/mol
Synonyms	1-([5-[4-Methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl]carbonyl)piperidine-4-carbonitrile; 1-((5-(4-Methyl-5-(trifluoromethyl)isoxazol-3-yl)thiophene-2-carbonyl)piperidine-4-carbonitrile; 4-Cyano-1-{[5-(4-methyl-5-trifluoromethyl-3-isoxazolyl)-2-thienyl]carbonyl}piperidine; [5-(4-Methyl-5-trifluoromethyl-3-isoxazolyl)-2-thienyl]-4-cyanopiperidin-1-yl-methanone
EINECS	Contact for details

Quality Control

Every batch of 4-Piperidinecarbonitrile, 1-[[5-[4-Methyl-5-(Trifluoromethyl)-3-Isoxazolyl]-2-Thienyl]Carbonyl]- is manufactured under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.