Description

Glp-1(7-36) Acetate is a synthetic peptide analog of the naturally occurring glucagon-like peptide-1, a key incretin hormone involved in glucose metabolism. This high-purity acetate salt form offers enhanced stability and is critical for research and development in metabolic disease therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on diabetes, obesity, and related endocrine disorder research.

Application

• Pharmaceutical Reference Standard: Serves as a critical benchmark for the identification, purity assessment, and quantification of GLP-1 analogs in drug development and quality control processes.
• Biochemical Research: Used in in vitro and ex vivo studies to investigate GLP-1 receptor (GLP-1R) signaling pathways, insulin secretion mechanisms, and β-cell function.
• Preclinical Development: Essential for formulation studies, stability testing, and pharmacokinetic/pharmacodynamic (PK/PD) modeling of next-generation GLP-1-based therapies.
• Cell Culture & Assay Development: Employed as a potent agonist in cell-based assays to screen for GLP-1R activity and to develop diagnostic tools for metabolic disorders.
• Academic Research: A fundamental tool for universities and research institutes studying endocrinology, physiology, and the pathophysiology of diabetes and obesity.

Basic Information

Product Name	Glp-1(7-36) Acetate
CAS No.	1119517-19-9
Molecular Formula	C149H226N40O47 • xC2H4O2
Molecular Weight	~3298.7 g/mol (free base)
Synonyms	Glucagon-like peptide 1 (7-36) amide acetate; GLP-1 (7-36) amide acetate; Incretin hormone fragment acetate; GLP-1 amide (7-36) acetate; H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 acetate; GLP-1 I acetate; Tirzepatide impurity standard
EINECS	Contact for details

Quality Control

Our Glp-1(7-36) Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including reversed-phase HPLC for purity, mass spectrometry for identity confirmation, and tests for related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC/IC)	3.0 - 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.