Description

trans-1-(Boc-Amino)-4-(4-Methyl-1-Piperazinyl)Cyclohexane, 97% is a high-purity, protected amine derivative featuring a cyclohexane scaffold substituted with a Boc-protected amino group and a 4-methylpiperazine moiety. This compound is a critical pharmaceutical intermediate and building block in medicinal chemistry, valued for its role in constructing complex molecules with specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in areas requiring advanced amine chemistry and heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific amine and piperazine functionalities into molecular scaffolds.
• Peptidomimetics Synthesis: Serves as a constrained, non-natural amino acid analog for creating peptide-like molecules with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying biological pathways and protein interactions.
• Ligand Development: Useful for constructing ligands for G-protein coupled receptors (GPCRs) and other biological targets where the piperazine moiety is a common pharmacophore.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	trans-1-(Boc-Amino)-4-(4-Methyl-1-Piperazinyl)Cyclohexane, 97%
CAS No.	1119283-74-7
Molecular Formula	C16H31N3O2
Molecular Weight	297.44 g/mol
Synonyms	trans-1-[(tert-Butoxycarbonyl)amino]-4-(4-methyl-1-piperazinyl)cyclohexane; 1-N-Boc-trans-1,4-cyclohexanediamine mono-4-methylpiperazine derivative; 4-Methyl-1-piperazinyl-cyclohexylamine, N-Boc-protected; tert-Butyl N-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]carbamate; Boc-trans-ACPC(4-Methylpiperazine); trans-N-Boc-4-(4-Methylpiperazino)cyclohexylamine
EINECS	Contact for details

Quality Control

Our trans-1-(Boc-Amino)-4-(4-Methyl-1-Piperazinyl)Cyclohexane is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.