Description

1-(4-(3-Methoxy-4-Nitrophenyl)Piperazin-1-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and nitrophenyl structural motifs. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis specialists requiring reliable, high-quality building blocks for complex molecular assembly.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially those with piperazine-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex organic molecules in custom synthesis and process development.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in API manufacturing.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands for biochemical assays.

Basic Information

Product Name	1-(4-(3-Methoxy-4-Nitrophenyl)Piperazin-1-Yl)Ethanone
CAS No.	1116229-11-8
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	1-[4-(3-Methoxy-4-nitrophenyl)piperazin-1-yl]ethanone; 1-(4-(3-Methoxy-4-nitrophenyl)-1-piperazinyl)ethanone; Ethanone, 1-[4-(3-methoxy-4-nitrophenyl)-1-piperazinyl]-; 1-(4-(3-Methoxy-4-nitrophenyl)piperazin-1-yl)ethan-1-one; 3-Methoxy-4-nitrophenylpiperazin-1-yl ethanone; 1116229-11-8; CAS 1116229-11-8
EINECS	Contact for details

Quality Control

Our 1-(4-(3-Methoxy-4-Nitrophenyl)Piperazin-1-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.