Description

Imidodicarbonic Acid, 2-[3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyrazinyl]-, 1,3-Bis(1,1-Dimethylethyl) Ester is a sophisticated, high-purity boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical protected boronic acid building block, enabling precise cross-coupling reactions essential for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams in the development of active pharmaceutical ingredients (APIs) and novel organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a protected precursor for introducing the 3-methoxy-5-pyrazinylboronic acid moiety into target molecules for drug discovery.
• Ligand and Catalyst Development: Used in the research and synthesis of novel ligands and organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers requiring specific heterocyclic boronic ester functionalities.
• Process Chemistry & Scale-Up: Provides a stable, handleable form of a reactive boronic acid for optimized manufacturing processes of complex molecules.
• Chemical Biology & Probe Development: Useful for creating molecular probes and tagged compounds for biological target identification and study.

Basic Information

Product Name	Imidodicarbonic Acid, 2-[3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyrazinyl]-, 1,3-Bis(1,1-Dimethylethyl) Ester
CAS No.	1111638-28-8
Molecular Formula	C21H32BN3O6
Molecular Weight	433.31 g/mol
Synonyms	2-(3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-yl)-1,3-di-tert-butyl imidodicarbonate; Di-tert-butyl 2-[3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyrazinyl]imidodicarbonate; 3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-yl N,N-Bis(tert-butoxycarbonyl)amine; BOC-Protected 3-Methoxy-5-pyrazinylboronic Acid Pinacol Ester; (3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-yl)carbamic Acid Di-tert-butyl Ester; Di-tert-butyl N-[3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-yl]imidodicarbonate
EINECS	Contact for details

Quality Control

Our production of this advanced boronic ester adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool environment. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.