Description

3-Chloro-5H-Pyrrolo[2,3-B]Pyrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific heterocyclic frameworks for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its fused pyrrolopyrazine structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific halogenated heterocycle.

Basic Information

Product Name	3-Chloro-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	1111638-10-8
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	3-Chloro-5H-pyrrolo[2,3-b]pyrazine; 3-Chloro-5H-pyrrolo[2,3-b]pyrazine; 5H-Pyrrolo[2,3-b]pyrazine, 3-chloro-; 3-Chloro-5H-pyrrolo[2,3-b]pyrazine (CAS 1111638-10-8); 3-Chloro-5H-pyrrolo[2,3-b]pyrazine, 95+%; 3-Chloro-5H-pyrrolo[2,3-b]pyrazine, 97%; 3-Chloro-5H-pyrrolo[2,3-b]pyrazine, 98%
EINECS	Contact for details

Quality Control

Our 3-Chloro-5H-Pyrrolo[2,3-B]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.