Description

3-(3-Phenylpiperazin-1-Yl)Pyrazin-2-Amine CAS NO 1111598-17-4 is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining pyrazine and phenylpiperazine moieties. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential as a key building block in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Critical intermediate in the research and synthesis of novel central nervous system (CNS) active compounds, including potential antipsychotics and antidepressants.
• Key building block for the development of receptor ligands and enzyme inhibitors targeting specific biological pathways.
• Used in medicinal chemistry research for structure-activity relationship (SAR) studies to optimize drug candidate properties.
• Precursor in the synthesis of complex heterocyclic libraries for high-throughput screening in drug discovery.
• Employed in academic and industrial R&D for investigating new chemical entities (NCEs) with potential pharmacological activity.

Basic Information

Product Name	3-(3-Phenylpiperazin-1-Yl)Pyrazin-2-Amine
CAS No.	1111598-17-4
Molecular Formula	C14H17N5
Molecular Weight	255.32 g/mol
Synonyms	3-(3-Phenyl-1-piperazinyl)-2-pyrazinamine; 2-Pyrazinamine, 3-(3-phenyl-1-piperazinyl)-; 3-(3-Phenylpiperazin-1-yl)pyrazin-2-amine; N-(3-Phenylpiperazin-1-yl)pyrazin-2-amine; 1111598-17-4; 3-(3-phenylpiperazin-1-yl)pyrazin-2-amine
EINECS	Contact for details

Quality Control

Our 3-(3-Phenylpiperazin-1-Yl)Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.