Description

2-(4-Ethylpiperazin-1-Yl)-1,3-Benzothiazol-6-Ol is a high-purity, advanced pharmaceutical intermediate featuring a benzothiazole core functionalized with a piperazine moiety. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies and contract research organizations (CROs) need it for the development of potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• As a key synthetic intermediate in the research and development of new chemical entities (NCEs) for pharmaceutical applications.
• In medicinal chemistry for the design and synthesis of benzothiazole-based compounds with potential biological activity.
• As a precursor for active pharmaceutical ingredients (APIs) targeting neurological and psychiatric conditions.
• For use in academic and industrial R&D programs focused on kinase inhibitors or receptor modulators.
• In the synthesis of fluorescent probes or diagnostic agents due to the photophysical properties of the benzothiazole scaffold.
• As a reference standard in analytical method development and quality control within pharmaceutical manufacturing.

Basic Information

Product Name	2-(4-Ethylpiperazin-1-Yl)-1,3-Benzothiazol-6-Ol
CAS No.	1105189-67-0
Molecular Formula	C₁₃H₁₇N₃OS
Molecular Weight	263.36 g/mol
Synonyms	6-Hydroxy-2-(4-ethyl-1-piperazinyl)benzothiazole; 2-(4-Ethyl-1-piperazinyl)-6-hydroxy-1,3-benzothiazole; 2-(4-Ethylpiperazin-1-yl)-1,3-benzothiazol-6-ol; 6-Hydroxy-2-(4-ethylpiperazin-1-yl)-1,3-benzothiazole; 2-(4-Ethylpiperazino)-6-hydroxybenzothiazole; Benzothiazol-6-ol, 2-(4-ethyl-1-piperazinyl)-; 1105189-67-0
EINECS	Contact for details

Quality Control

Our 2-(4-Ethylpiperazin-1-Yl)-1,3-Benzothiazol-6-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.