Description

1-(Methylnitrosoamino)-2-Propanol is a specialized organic compound belonging to the nitrosamine class. This high-purity chemical is critical for research and development, particularly in analytical chemistry and toxicology studies. It serves as a valuable reference standard and intermediate for scientists and quality control laboratories in the pharmaceutical, chemical, and academic sectors.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the accurate quantification and identification of nitrosamine impurities in pharmaceutical products and chemical syntheses.
• Pharmaceutical Research: Employed in method development and validation studies for detecting and monitoring genotoxic nitrosamine impurities to ensure drug safety and regulatory compliance (e.g., for ICH M7, FDA, EMA guidelines).
• Toxicological Studies: Serves as a key compound in metabolic, carcinogenicity, and mutagenicity research to understand the biological impact of nitrosamine exposure.
• Chemical Synthesis Intermediate: Acts as a building block or precursor in the research-scale synthesis of more complex molecules for specialized applications.
• Quality Control & Assurance: Essential for spiking experiments and recovery studies in laboratory quality control protocols to ensure analytical system suitability.

Basic Information

Product Name	1-(Methylnitrosoamino)-2-Propanol
CAS No.	1104874-94-3
Molecular Formula	C4H10N2O2
Molecular Weight	118.13 g/mol
Synonyms	N-Nitroso-N-methylisopropanolamine; 2-Hydroxypropyl(methyl)nitrosamine; N-Methyl-N-nitrosoisopropanolamine; MNIP; 1-(Methylnitrosoamino)propan-2-ol; Isopropanol, 1-(methylnitrosoamino)-; N-Nitroso-N-methyl-2-hydroxypropylamine
EINECS	Contact for details

Quality Control

Our 1-(Methylnitrosoamino)-2-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for use as a reference standard. A detailed Certificate of Analysis (COA) with batch-specific data is provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.