Description

tert-Butyl 2,2-Dimethyl-3-Oxopiperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the piperazine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• API Synthesis: Serves as a crucial precursor in the manufacturing of complex Active Pharmaceutical Ingredients (APIs) requiring the piperazine pharmacophore.
• Medicinal Chemistry R&D: Used extensively in research laboratories for structure-activity relationship (SAR) studies and lead optimization during drug discovery.
• Process Chemistry: Employed in the development and scale-up of efficient, cost-effective synthetic routes for target molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	tert-Butyl 2,2-Dimethyl-3-Oxopiperazine-1-Carboxylate
CAS No.	1104383-06-3
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	1-Boc-2,2-dimethyl-3-oxopiperazine; tert-Butyl 2,2-dimethyl-3-oxo-1-piperazinecarboxylate; 3-Oxo-2,2-dimethylpiperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2,2-dimethyl-3-oxopiperazine; Boc-2,2-dimethyl-3-oxopiperazine; 2,2-Dimethyl-3-oxo-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,2-Dimethyl-3-Oxopiperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality control protocols are designed to meet the stringent requirements of our global clientele in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.