Description

1-(4-Chlorobenzoyl)Piperidine-2-Carboxylic Acid is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its role as a versatile precursor for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Academic Research: A valuable reagent for universities and research institutes studying novel heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	1-(4-Chlorobenzoyl)Piperidine-2-Carboxylic Acid
CAS No.	1103295-13-1
Molecular Formula	C13H14ClNO3
Molecular Weight	267.71 g/mol
Synonyms	1-[(4-Chlorophenyl)carbonyl]piperidine-2-carboxylic acid; 2-Piperidinecarboxylic acid, 1-(4-chlorobenzoyl)-; 1-(4-Chlorobenzoyl)-2-piperidinecarboxylic Acid; 4-Chloro-N-(2-carboxypiperidin-1-yl)benzamide; (4-Chlorobenzoyl)pipecolinic Acid; 1-(p-Chlorobenzoyl)piperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Chlorobenzoyl)Piperidine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We operate under a quality system designed to meet the exacting standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.