Description

4-Bromo-2-(4-Methyl-1-Piperazinyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoic acid core substituted with bromine and a methylpiperazinyl group. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical research and development organizations, as well as fine chemical manufacturers, need this material for creating novel drug candidates, process development, and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block for constructing complex API molecules, leveraging its bromine and piperazine functional groups for further chemical modifications.
• Medicinal Chemistry & Drug Discovery: Used in research laboratories for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable synthetic routes for pharmaceutical manufacturing.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use in the development of biochemical probes and tools for studying biological pathways and target engagement.

Basic Information

Product Name	4-Bromo-2-(4-Methyl-1-Piperazinyl)Benzoic Acid
CAS No.	1099687-04-3
Molecular Formula	C₁₂H₁₅BrN₂O₂
Molecular Weight	299.17 g/mol
Synonyms	4-Bromo-2-(4-methylpiperazin-1-yl)benzoic acid; 2-(4-Methyl-1-piperazinyl)-4-bromobenzoic acid; Benzoic acid, 4-bromo-2-(4-methyl-1-piperazinyl)-; 1099687-04-3; 4-Bromo-2-(4-methylpiperazino)benzoic acid; 4-Bromo-2-(N-methylpiperazino)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(4-Methyl-1-Piperazinyl)Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting compliance with internal quality standards and regulatory expectations for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.