Description

2-(4-Cyclobutanecarbonylpiperazin-1-Yl)Ethan-1-Amine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core functionalized with a cyclobutanecarbonyl group and an aminoethyl side chain. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Process Chemistry & Scale-Up: Employed in route scouting and the development of robust, scalable synthetic pathways for API manufacturing.
• Ligand & Building Block Synthesis: Functions as a versatile scaffold for creating specialized ligands, catalysts, or more complex heterocyclic compounds in organic synthesis.

Basic Information

Product Name	2-(4-Cyclobutanecarbonylpiperazin-1-Yl)Ethan-1-Amine
CAS No.	1094793-21-1
Molecular Formula	C11H21N3O
Molecular Weight	211.31 g/mol
Synonyms	1-[2-Aminoethyl]-4-(cyclobutanecarbonyl)piperazine; 2-[4-(Cyclobutanecarbonyl)piperazin-1-yl]ethanamine; N-(2-Aminoethyl)-N'-(cyclobutanecarbonyl)piperazine; 2-(4-Cyclobutanoylpiperazin-1-yl)ethanamine; 1094793-21-1; 1-Piperazineethanamine, 4-(cyclobutanecarbonyl)-; Ethan-1-amine, 2-(4-cyclobutanecarbonylpiperazin-1-yl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Cyclobutanecarbonylpiperazin-1-Yl)Ethan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.