Description

[4-(Morpholin-4-Yl)-2-(Trifluoromethyl)Phenyl]Methanamine is a high-purity, functionalized aniline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for the development of novel pharmaceuticals and agrochemicals, where its unique trifluoromethyl and morpholine substituents impart desirable biological and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• As a key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Utilized as a precursor for agrochemicals, including herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Serves as a building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Used in the research and development of functional materials, such as ligands for catalysts or components in organic electronics.
• Employed in custom synthesis and contract manufacturing for clients requiring specific, high-value chemical entities.

Basic Information

Product Name	[4-(Morpholin-4-Yl)-2-(Trifluoromethyl)Phenyl]Methanamine
CAS No.	1094436-83-5
Molecular Formula	C12H15F3N2O
Molecular Weight	260.26 g/mol
Synonyms	1-[4-(Morpholin-4-yl)-2-(trifluoromethyl)phenyl]methanamine; 4-(4-(Aminomethyl)-3-(trifluoromethyl)phenyl)morpholine; (4-Morpholino-2-trifluoromethylphenyl)methanamine; 2-(Trifluoromethyl)-4-morpholinobenzylamine; 4-(Aminomethyl)-2-trifluoromethylphenyl morpholine; 4-Morpholino-α,α,α-trifluoro-o-toluidine (related); Benzenemethanamine, 4-morpholino-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our [4-(Morpholin-4-Yl)-2-(Trifluoromethyl)Phenyl]Methanamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support development and commercial projects requiring material that meets ICH guidelines and specific client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.