Description

2-(4-Ethyl-Piperazin-1-Yl)-2-(4-Methoxy-Phenyl)-Ethylamine Dihydrochloride is a high-purity, pharmaceutically relevant chemical intermediate characterized by its dihydrochloride salt form, which enhances stability and handling properties. This compound is of significant value for research and development in medicinal chemistry, particularly for its structural features that are conducive to creating bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, including potential candidates for central nervous system (CNS) and other receptor-targeted applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds, particularly those targeting GPCRs or other neurological receptors.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Preclinical Development: Utilized in the production of compounds for pharmacological and toxicological evaluation during early-stage drug development.
• Custom Synthesis: A key starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	2-(4-Ethyl-Piperazin-1-Yl)-2-(4-Methoxy-Phenyl)-Ethylamine Dihydrochloride
CAS No.	1094390-60-9
Molecular Formula	C15H26Cl2N3O
Molecular Weight	335.29 g/mol
Synonyms	2-(4-Ethylpiperazin-1-yl)-2-(4-methoxyphenyl)ethan-1-amine dihydrochloride; 1-[2-Amino-2-(4-methoxyphenyl)ethyl]-4-ethylpiperazine dihydrochloride; 4-Methoxy-α-[(4-ethyl-1-piperazinyl)methyl]benzenemethanamine dihydrochloride; 2-(4-Methoxyphenyl)-2-(4-ethyl-1-piperazinyl)ethylamine dihydrochloride; (4-Methoxyphenyl)[(4-ethylpiperazin-1-yl)methyl]methanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Ethyl-Piperazin-1-Yl)-2-(4-Methoxy-Phenyl)-Ethylamine Dihydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.