Description

4-(3-Aminophenyl)Piperazin-2-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its piperazine core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its aromatic amine functionality allows for further derivatization.
• Ligand Synthesis: Employed in the creation of chelating ligands for catalysis and metal-organic frameworks (MOFs) in material science applications.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal or mechanical properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments, leveraging its amine group for coupling reactions.
• Bioconjugation Chemistry: The reactive amine group makes it suitable for linking biomolecules in probe and diagnostic reagent development.

Basic Information

Product Name	4-(3-Aminophenyl)Piperazin-2-One
CAS No.	1094352-46-1
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	1-(3-Aminophenyl)piperazin-2-one; 3-Amino-1-(2-oxopiperazin-1-yl)benzene; 1-(3-Aminophenyl)-2-piperazinone; 4-(3-Aminophenyl)-2-piperazinone; 1-(m-Aminophenyl)piperazin-2-one; 2-Piperazinone, 1-(3-aminophenyl)-; 1094352-46-1; 4-(3-Aminophenyl)-2-piperazinone
EINECS	Contact for details

Quality Control

Our 4-(3-Aminophenyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.