Description

1-Propanol, 2-[Ethyl[[5-[[6-Methyl-3-(1H-Pyrazol-4-Yl)Imidazo[1,2-A]Pyrazin-8-Yl]Amino]-3-Isothiazolyl]Methyl]Amino]-2-Methyl- is a high-purity, complex heterocyclic organic compound designed for advanced research and development. This specialized chemical serves as a critical building block or intermediate in the synthesis of novel pharmaceutical candidates, particularly in oncology and targeted therapies. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates to accelerate drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the route development and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential tool compound for probing specific biological pathways and protein functions in vitro.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage drug development services.

Basic Information

Item	Details
Product Name	1-Propanol, 2-[Ethyl[[5-[[6-Methyl-3-(1H-Pyrazol-4-Yl)Imidazo[1,2-A]Pyrazin-8-Yl]Amino]-3-Isothiazolyl]Methyl]Amino]-2-Methyl-
CAS No.	1094069-99-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-[Ethyl[[5-[[6-Methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-isothiazolyl]methyl]amino]-2-methyl-1-propanol; UNII-7V2T2V6H0P; 7V2T2V6H0P; 2-Methyl-2-({[5-({6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl}amino)-1,2-thiazol-3-yl]methyl}ethylamino)propan-1-ol; CS-0776; AZD-3759 Intermediate; EGFR Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development under quality agreements and can supply material suitable for use in cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.