Description

Methyl 3-Bromo-6-Iodopyrazine-2-Carboxylate is a high-purity, multi-halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique reactivity profile, enabling the precise construction of complex heterocyclic scaffolds essential for modern research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and optimization of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for the synthesis of functionalized pyrazine-based polymers and organic electronic materials.
• Chemical Biology: Employed as a versatile scaffold for creating molecular probes and tool compounds.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: A valuable starting material for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	Methyl 3-Bromo-6-Iodopyrazine-2-Carboxylate
CAS No.	1093383-16-4
Molecular Formula	C6H4BrIN2O2
Molecular Weight	342.92 g/mol
Synonyms	Methyl 3-bromo-6-iodopyrazine-2-carboxylate; 3-Bromo-6-iodopyrazine-2-carboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 3-bromo-6-iodo-, methyl ester; Methyl 3-bromo-6-iodo-2-pyrazinecarboxylate; 1093383-16-4; 3-Bromo-6-iodo-2-pyrazinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-6-Iodopyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.